CBD'S Entourage Effect - The Right Mix of CBD, THC, and other Cannabinoids

by BM Innovations on October 09, 2023

Hemp plants contain more than several different phytocannabinoids . These act on your body’s endocannabinoid system (ECS), which regulates and balances a number of functions and processes. Cannabidiol (CBD) and tetrahydrocannabinol (THC) are two of the most well-researched phytocannabinoids. 


What is the Entourage Effect? 

The term CBD entourage effect was first coined in 1998 by Dr. Ben Shabat coined. The concept was primarily developed by Dr. Etahan Russo explained and expanded. 

Research suggests that taking pure CBD together - along with other natural compounds in the cannabis plant known as terpenes or terpenoids - is more effective than taking CBD alone. 

Important  terpenes naturally found in hemp: 

  • myrcene 
  • pinen 
  • limes 
  • caryophyllene 

Simply defined, the entourage effect is the hypothesis that the complete spectrum of the cannabis plant works best together - the interaction between all of the plant's compounds, such as phytocannabinoids and terpenes, coming together to maximize their benefits. The word usually refers to natural remedies that contain a variety of substances that work together to have a specific effect on a person's health, such as reducing inflammation or relieving anxiety. 


What are cannabiniods 

Cannabinoids are compounds found naturally in the Cannabis sativa plant. Roughly 480 distinct compounds found in he hemp plant are classified as cannabinoids. 

Cannabidiol (CBD), which accounts for roughly 40% of the plant resin extract, well known for its therapeutic benefits. Another major component is delta-9-tetrahydrocannabinol (9-THC), which is the major psychoactive element in cannabis, these two cannabiniods are the most well-known of all.  


What do cannabinoids do in the body? 

Once cannabinoids enter the human body, their main job is to interact with the cannabinoid receptors. Cannabinoid receptors play an important role in the endocannabinoid system (ECS). The other two are endocannabinoids (which play the role of neurotransmitters) and enzymes (which are responsible for breaking down cannabinoids that have served their purpose). 

The two most well-known endocannabinoid receptors are the CB1 and CB2 receptors. CB1 receptors are found in large numbers in the brain and central nervous system, while CB2 receptors are primarily associated with the immune system.  

Every human has an ECS and produces endocannabinoids that are able to bind to and activate the CB1 and CB2 receptors. Through these interactions, endocannabinoids can influence various processes, e.g. B. sleep, mood, stress and much more.  


Therapeutic benefits of CBD 

CBD as a medicine is already being used to treat pain from multiple sclerosis and epilepsy in children. Clinical studies suggest that the uses of pure CBD oil go well beyond that. In particular, the influence of CBD on receptors that play a role in depression, sleep disorders or pain justify further studies. CBD can be used for he following disorders: 

  • Pains 
  • inflammation 
  • emotions and mood 
  • the perception of fears 
  • Inadequate sleep/insomnia  
  • memory disorder  
  • appetite and digestion 


CBD and THC 

Cannabidiol (CBD) and tetrahydrocannabinol (THC) are two of the most well-researched phytocannabinoids. Tetrahydrocannabinol (THC) is a cannabinoid that, unlike CBD, has an intoxicating effect and is responsible for the "high" one usually associates with cannabis. 

It causes brain cells to release dopamine, a chemical that induces feelings of euphoria. It also impedes information processing in the hippocampus, the area of ​​the brain responsible for forming new memories, while CBD on he other hand doesn't cause any of these effects or induce euphoric feelings.  

To your surprise, just like CBD, THC is also available in the form of oils, snacks, ointments, and more. However, when both substances interact with the body's endocannabinoid system, they have very different effects. In fact, they are often used in commercial products in a synergistic combination to achieve various medicinal benefits. 



The entourage effect is a fascinating hypothesis that depicts the wide range of compounds and phytochemicals found in cannabis plants, as well as the various ways in which they can interact to increase well-being and deliver various advantages. We expect that as more information becomes available, there will be a greater variety of CBD products available, as well as more chances for positive impacts on the body.